Alice 12 mg Tablet

Antiparasitic for:

• Strongyloidiasis (threadworm of the gut)
• Scabies (crusted scabies, or when creams fail or many people are affected)
• Head lice (lotion; oral in resistant cases)
• Onchocerciasis (river blindness), lymphatic filariasis (with albendazole, in programmes)
• Cream 1%: inflammatory lesions of rosacea

Oral — single dose of about 200 micrograms/kg (adults and children 15 kg and over):

• 15–24 kg: 3 mg; 25–35 kg: 6 mg; 36–50 kg: 9 mg; 51–65 kg: 12 mg; 66–79 kg: 15 mg; 80 kg and over: 200 microgram/kg.
• Strongyloidiasis: single dose (some guidelines repeat on day 2 or after 2 weeks).
• Scabies: 200 microgram/kg, repeated after 7–14 days; treat close contacts at the same time and wash bedding/clothes.
• Take on an empty stomach with water (1 hour before breakfast).

Rosacea cream 1%: apply once daily to the face for up to 4 months.

• Not for children under 15 kg.

• Allergy to ivermectin
• Children under 15 kg (oral)
• Conditions with a damaged blood–brain barrier (e.g. meningitis)

Common: dizziness, nausea, diarrhoea, tiredness, itching.

Mazzotti-type reaction (in filarial infections): fever, itching, rash, joint pain, swollen glands, low blood pressure.

Rare but serious: serious brain reactions (confusion, coma) in people heavily infected with Loa loa; severe skin reactions; liver inflammation.

Cream: skin burning, irritation, dryness.

• People from central Africa may need testing for Loa loa before treatment.
• Scabies itching may continue for 2–4 weeks after successful treatment.
• Not effective against viral infections (including COVID-19).

Not recommended in pregnancy unless clearly needed (topical options preferred for scabies). Small amounts pass into milk; usually avoid during breastfeeding for the first week after birth.

• Warfarin (INR may rise — monitor)
• Drugs that depress the brain (alcohol, benzodiazepines, barbiturates) — caution

Rash, swelling, headache, dizziness, nausea, vomiting, unsteadiness, seizures, coma. Seek medical care.

Store below 30°C.