Alphapress XR-5 Tablet

Alpha-1 blocker for:

• High blood pressure
• Benign prostatic hyperplasia (urinary symptoms)
• Raynaud's phenomenon
• Scorpion sting envenomation (specialist/emergency use, common in South Asia)
• Nightmares in PTSD (off-label)

Hypertension: first dose 0.5 mg at bedtime (to avoid fainting), then 0.5 mg two to three times daily for 3–7 days, increased gradually to 1–5 mg two to three times daily (max 20 mg/day).

BPH / Raynaud's: 0.5 mg twice daily, increased to 1–2 mg twice daily.

Scorpion sting (hospital): adults 1 mg; children 30 microgram/kg — repeated every 3–6 hours as per protocol.

• Allergy to prazosin or other quinazolines (doxazosin, terazosin)
• History of fainting on urination (micturition syncope)
• Heart failure due to mechanical obstruction (e.g. aortic stenosis)

Common: first-dose low blood pressure and fainting, dizziness, drowsiness, headache, weakness, palpitations, nausea, nasal congestion.

Less common: fluid retention, urinary frequency, blurred vision, dry mouth.

Rare: priapism, incontinence in women.

• Take the first dose at bedtime; rise slowly from sitting/lying.
• Avoid driving until you know how it affects you.
• Tell the eye surgeon before cataract surgery (floppy iris syndrome).
• Liver or kidney impairment, elderly: start low.

Use in pregnancy only if clearly needed. Small amounts in breast milk — caution.

• Other antihypertensives, diuretics, beta-blockers (marked first-dose low BP)
• PDE-5 inhibitors (sildenafil, tadalafil) — severe low BP
• Alcohol (dizziness)

Severe low blood pressure, drowsiness, shock. Lie flat with legs raised; emergency care.

Store below 30°C, protected from light.