Amlovas Tablet

Combination of a calcium-channel blocker and an ARB for high blood pressure not controlled by either alone, or to replace separate tablets.

Adults: one tablet once daily — amlodipine 5 mg + valsartan 80 mg, 5/160, 10/160, 5/320 or 10/320 mg.

• Increase after 1–2 weeks if needed; maximum 10/320 mg daily.
• With or without food, same time daily.
• Not for children under 18.

• Pregnancy
• Severe liver impairment, biliary cirrhosis or cholestasis
• Shock, severe aortic stenosis, unstable heart failure after a heart attack
• Use with aliskiren in diabetes or kidney impairment
• Allergy to dihydropyridines or valsartan

Common: ankle swelling, dizziness, headache, flushing, tiredness, nasopharyngitis.

Less common: low blood pressure, palpitations, raised potassium/creatinine, joint pain, cough.

Rare but serious: angioedema, kidney failure, severe low blood pressure, liver problems.

• Check potassium and kidney function periodically.
• Avoid dehydration; caution in heart failure, renal artery stenosis.

Contraindicated in pregnancy. Not recommended while breastfeeding.

• Potassium supplements, spironolactone, salt substitutes (high potassium)
• NSAIDs (reduced effect, kidney risk)
• Lithium (toxicity)
• ACE inhibitors, aliskiren (avoid combining)
• Simvastatin (limit 20 mg); clarithromycin, itraconazole, grapefruit (raise amlodipine)

Severe low blood pressure, fast heartbeat. Emergency care.

Store below 30°C, protected from moisture.