Ascova 400 mg Tablet

Bronchodilator (xanthine) for:

• Bronchial asthma
• Chronic obstructive pulmonary disease (COPD) and chronic bronchitis with bronchospasm

Adults: 400 mg two to three times daily (or as directed), for example 400 mg twice daily; maximum usually 1,200 mg/day.

Elderly / liver disease: 200 mg two to three times daily.

Children (over 6 years): about 6 mg/kg twice daily, as prescribed. Syrup dose by weight.

• Take after meals.
• Usually better tolerated than theophylline, but blood levels are not routinely needed.

• Allergy to doxophylline or other xanthines
• Acute heart attack, low blood pressure
• Breastfeeding

Common: nausea, stomach upset, headache, sleeplessness, irritability.

Less common: vomiting, palpitations, fast heartbeat, tremor.

Rare: irregular heartbeat, high blood sugar, seizures (at high levels).

• Use with caution in heart disease, high blood pressure, overactive thyroid, peptic ulcer, liver or kidney disease and the elderly.
• Do not combine with other xanthines (theophylline, aminophylline) or large amounts of caffeine.

Avoid in pregnancy unless clearly needed. Contraindicated while breastfeeding.

• Other xanthines, caffeine (more side effects)
• Erythromycin, ciprofloxacin, cimetidine, allopurinol (may raise levels)
• Phenytoin, rifampicin, smoking (may reduce levels)

Severe nausea, vomiting, fast irregular heartbeat, agitation, seizures. Emergency care.

Store below 30°C, protected from light.