Clotrizole 10 mg/gm Cream

Imidazole antifungal for:

• Cream/powder/solution 1%: ringworm (body, groin, feet — athlete's foot), skin candidiasis, nappy rash with Candida, pityriasis versicolor, fungal infection of skin folds
• Vaginal tablet/cream: vaginal thrush (candidiasis)
• Ear drops/solution: fungal ear infection (otomycosis)
• Mouth paint/troche: oral thrush

Skin cream 1%: apply thinly 2–3 times daily; continue for at least 2 weeks after symptoms clear (athlete's foot at least 1 month total; pityriasis 1–3 weeks).

Vaginal tablet: 500 mg once at bedtime (single dose), or 200 mg nightly for 3 nights, or 100 mg nightly for 6 nights; vaginal cream 2% once nightly for 3 days (10% single dose). Treat the partner's genital area with cream if symptomatic.

Ear drops 1%: 2–3 drops 3–4 times daily for 14 days.

Oral paint/troche: apply/dissolve 10 mg troche in the mouth 3–5 times daily for 7–14 days.

• Allergy to clotrimazole or imidazoles

Topical: local burning, stinging, itching, redness, peeling.

Vaginal: local burning, irritation, abdominal cramps (uncommon).

Rare: allergic reactions (rash, swelling).

• Keep away from eyes.
• Vaginal products may damage latex condoms and diaphragms — use alternative contraception for 5 days after treatment.
• Recurrent thrush (4 or more times a year), first episode, or symptoms in girls under 16 / women over 60 need medical review.
• Keep skin dry; avoid sharing towels.

Topical and vaginal use is considered safe in pregnancy (insert vaginal tablets by hand, not applicator, late in pregnancy). Compatible with breastfeeding.

Minimal with topical use. Vaginal use may slightly increase tacrolimus levels.

Not expected with topical use. If swallowed: stomach upset — seek advice.

Store below 30°C.