Cytomis 200 Tablet

Prostaglandin E1 analogue used for:

• Prevention and treatment of postpartum haemorrhage (when oxytocin is not available)
• Obstetric and gynaecological uses under medical supervision (as per national guidelines): induction of labour, management of miscarriage, cervical preparation before procedures
• Prevention and treatment of NSAID-induced stomach and duodenal ulcers

Obstetric uses must only be done under medical supervision according to national guidelines.

• Postpartum haemorrhage prevention: 600 micrograms by mouth immediately after the birth of the baby (when oxytocin is unavailable); treatment: 800 micrograms under the tongue.
• NSAID ulcer prevention: 200 micrograms two to four times daily with food (with the NSAID).
• NSAID ulcer treatment: 800 micrograms daily in 2–4 divided doses for 4–8 weeks.

• Pregnancy when continuation is wanted (for ulcer prevention/treatment) — can cause miscarriage, premature birth and birth defects
• Allergy to prostaglandins
• Previous caesarean section or uterine scar (for labour induction — higher risk of uterine rupture; specialist decision)

Common: diarrhoea, abdominal pain, nausea, vomiting, wind, headache; shivering and fever (especially after obstetric doses).

Gynaecological: uterine cramps, vaginal bleeding.

Serious: heavy bleeding, uterine rupture (in labour, especially with a scar), severe dehydration from diarrhoea.

• Women of child-bearing age using it for ulcers must use effective contraception and must not be pregnant.
• Heart or blood-vessel disease, inflammatory bowel disease, dehydration: caution.
• Keep out of reach of others; must not be used without medical supervision in pregnancy.

Contraindicated in pregnancy for non-obstetric uses. Obstetric use only under medical supervision. Small amounts pass into milk — may cause diarrhoea in the baby; usually compatible after postpartum doses.

• Magnesium-containing antacids (worsen diarrhoea)
• Oxytocin (enhanced uterine effect — monitor)
• NSAIDs (used together intentionally for ulcer protection)

Sedation, tremor, seizures, breathing difficulty, abdominal pain, diarrhoea, fever, palpitations, low blood pressure, slow heartbeat. Seek emergency care.

Store below 25–30°C in the original blister, protected from moisture (degrades in humidity).