Beximco Pharmaceuticals Ltd.

Diapro 80 mg Tablet

Name: Diapro 80 mg Tablet
Brand: Beximco Pharmaceuticals Ltd.
SKU: 186-0203-015

Gliclazide · 80 mg

Medicine information: uses, dosage, side effects ↓

Prescription required Tablet

Also available as: 30 mg (Tablet)60 mg (Tablet)

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Gliclazide 80 mg TabletOrion Life Sciences · 10 tablets ৳76

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Product details

Generic name: Gliclazide
Strength: 80 mg
Dosage form: Tablet
Manufacturer / brand: Beximco Pharmaceuticals Ltd.
SKU: 186-0203-015

Medicine information: Gliclazide

Indications

Sulphonylurea medicine for type 2 diabetes:

Lowers blood sugar when diet, exercise and weight loss are not enough
Used alone or with metformin, other tablets or insulin

Dosage & administration

Immediate-release (80 mg): start 40–80 mg daily with breakfast; increase gradually; doses above 160 mg are split into two; maximum 320 mg/day.

Modified-release (30/60 mg MR): start 30 mg once daily with breakfast; increase every 4 weeks if needed; maximum 120 mg once daily.

Take with breakfast; swallow MR tablets whole (the 60 mg MR can be halved if scored).
Do not skip meals after taking it.
Elderly and kidney impairment: start low.

Contraindications

Type 1 diabetes, diabetic ketoacidosis, diabetic coma
Severe kidney or liver impairment
Allergy to gliclazide or other sulphonylureas/sulphonamides
Use with miconazole (oral)
Pregnancy and breastfeeding (insulin is used instead)

Side effects

Most important: low blood sugar (hypoglycaemia) — sweating, shaking, hunger, fast heartbeat, confusion; more likely if meals are missed, with alcohol, exercise, kidney/liver disease or other diabetes drugs.

Common: stomach pain, nausea, indigestion, diarrhoea or constipation.

Less common: weight gain, rash, itching.

Rare: liver problems, jaundice, blood disorders, severe skin reactions, haemolytic anaemia (G6PD deficiency).

Precautions & warnings

Learn the signs of low blood sugar; carry sugar or glucose.
Regular meals; extra care with alcohol, fasting (e.g. Ramadan — dose adjustment needed), heavy exercise.
G6PD deficiency: risk of haemolysis.
Monitor blood sugar and HbA1c regularly.

Pregnancy & breastfeeding

Not recommended in pregnancy or breastfeeding; insulin is preferred.

Interactions

Miconazole, fluconazole (severe hypoglycaemia)
Beta-blockers (mask hypoglycaemia), ACE inhibitors, clarithromycin, NSAIDs, fluoroquinolones, alcohol (increase hypoglycaemia)
Steroids, thiazides, chlorpromazine, danazol (raise blood sugar)
Warfarin (effect may increase)

Overdose

Severe, prolonged low blood sugar (may last days) — give sugar if conscious and seek emergency care; hospital observation needed.

Storage

Store below 30°C.

This information is for general reference only. Always follow the dose prescribed by your doctor and ask a doctor or pharmacist before taking any medicine.