Healthcare Pharmaceuticals Ltd.

Dilatin 90 mg Tablet

Name: Dilatin 90 mg Tablet
Brand: Healthcare Pharmaceuticals Ltd.
SKU: 323-0197-022

Diltiazem Hydrochloride · 90 mg

Medicine information: uses, dosage, side effects ↓

Prescription required Tablet

Also available as: 120 mg (Tablet)

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Product details

Generic name: Diltiazem Hydrochloride
Strength: 90 mg
Dosage form: Tablet
Manufacturer / brand: Healthcare Pharmaceuticals Ltd.
SKU: 323-0197-022

Medicine information: Diltiazem Hydrochloride

Indications

Non-dihydropyridine calcium-channel blocker for:

Angina (including variant/Prinzmetal angina)
High blood pressure (sustained-release forms)
Rate control in atrial fibrillation/flutter; supraventricular tachycardia (injection, hospital)
Cream/gel 2%: chronic anal fissure

Dosage & administration

Angina: 60 mg three times daily (elderly: twice daily), increased up to 360 mg daily; or sustained-release 90–180 mg twice daily / 180–300 mg once daily.

Hypertension (SR): 90–120 mg twice daily or 180–360 mg once daily.

Anal fissure (2% cream): apply a pea-sized amount to the anal area twice daily for 6–8 weeks.

Swallow SR forms whole. Do not switch between brands of SR forms without advice.
Liver/kidney impairment and elderly: start low.

Contraindications

Slow heart rate, 2nd/3rd degree heart block or sick sinus syndrome (without pacemaker)
Left ventricular failure with lung congestion; cardiogenic shock; severe low blood pressure
Acute heart attack with heart failure
Use with ivabradine, dantrolene infusion, or with IV beta-blockers
Pregnancy

Side effects

Common: ankle swelling, headache, flushing, dizziness, slow heartbeat, tiredness, nausea, constipation.

Less common: heart block, palpitations, low blood pressure, rash, raised liver enzymes, gum overgrowth.

Rare but serious: severe skin reactions, worsening heart failure, liver injury; cream: local headache, anal itching.

Precautions & warnings

Heart failure or poor heart function: may worsen.
Liver or kidney impairment, elderly: lower doses.
Do not combine with beta-blockers without close monitoring.
Check pulse; report fainting or very slow pulse.

Pregnancy & breastfeeding

Contraindicated in pregnancy (animal studies). Avoid while breastfeeding.

Interactions

Beta-blockers, digoxin, amiodarone, ivabradine (slow heart rate/heart block)
Simvastatin, lovastatin, atorvastatin (muscle damage — limit doses)
Ciclosporin, tacrolimus, carbamazepine, midazolam, triazolam (levels rise)
Rifampicin (greatly reduces diltiazem)
Clopidogrel, apixaban/rivaroxaban (levels may change)

Overdose

Severe slow heartbeat, heart block, low blood pressure, heart failure. Emergency care.

Storage

Store below 30°C, protected from light and moisture.

This information is for general reference only. Always follow the dose prescribed by your doctor and ask a doctor or pharmacist before taking any medicine.