Drotaverine 40 mg Tablet

Smooth-muscle antispasmodic (PDE-4 inhibitor) for:

• Spasm of the gut — intestinal colic, irritable bowel syndrome
• Biliary colic, renal/ureteric colic (stones)
• Period pain (dysmenorrhoea)
• Spastic conditions of the bladder

Adults: 40–80 mg three times daily (maximum 240 mg/day).

Children 6–12 years: 40 mg one to two times daily (maximum 80 mg/day); not recommended under 6 years (tablets).

Injection (40 mg/2 ml): 40–80 mg IM/IV one to three times daily (health professional).

• Severe liver, kidney or heart failure (heart block)
• Allergy to drotaverine
• Children under 1 year (injection) / 6 years (tablets)
• Lactose intolerance (some tablets)

Uncommon: nausea, constipation, headache, dizziness, palpitations, low blood pressure.

Rare: allergic reactions (rash, swelling, anaphylaxis — mainly with injection), insomnia.

• Low blood pressure: caution, especially with IV injection (give slowly, patient lying down).
• May cause dizziness — avoid driving if affected.
• Persistent or worsening abdominal pain, fever, vomiting or blood in stool/urine need medical assessment.

Avoid in pregnancy unless clearly needed (limited data); not recommended in labour. Not recommended while breastfeeding.

• Levodopa (may reduce its anti-Parkinson effect)
• Other antispasmodics/papaverine (additive)

Heart rhythm disturbances (conduction blocks), low blood pressure. Supportive care.

Store below 30°C, protected from light.