Esoz 20 mg Tablet

Proton-pump inhibitor (PPI) that reduces stomach acid:

• Gastro-oesophageal reflux disease (GERD), heartburn, reflux oesophagitis
• Gastric and duodenal ulcers
• Helicobacter pylori eradication (with antibiotics)
• Prevention and healing of ulcers caused by NSAID painkillers
• Zollinger–Ellison syndrome
• Injection: when oral treatment is not possible; prevention of re-bleeding after endoscopy for bleeding ulcers

Adults:

• Reflux oesophagitis: 40 mg once daily for 4–8 weeks; maintenance 20 mg once daily.
• Heartburn (GERD symptoms): 20 mg once daily.
• H. pylori: 20 mg twice daily with two antibiotics for 7–14 days.
• NSAID ulcer prevention: 20 mg once daily.

Children (1–11 years): 10–20 mg once daily depending on weight, as prescribed.

• Take at least 30–60 minutes before a meal, usually before breakfast; swallow capsule/tablet whole (MUPS tablets may be dispersed in water).

• Allergy to esomeprazole or other PPIs
• Taking nelfinavir

Common: headache, abdominal pain, diarrhoea, constipation, wind, nausea.

Less common: dizziness, dry mouth, rash, sleep problems, swelling of ankles.

With long-term use: low magnesium, vitamin B12 deficiency, increased risk of bone fractures, gut infections (including C. difficile), stomach polyps.

Rare: severe skin reactions, kidney inflammation, liver problems, lupus-like rash.

• Rule out stomach cancer if there are alarm symptoms (weight loss, difficulty swallowing, vomiting blood, black stools).
• Use the lowest dose for the shortest time needed.
• Long-term use: check magnesium; consider bone health.
• Severe liver disease: maximum 20 mg daily.

Can be used in pregnancy if needed (limited data, no clear harm). Small amounts likely pass into breast milk; use only if necessary.

• Clopidogrel (effect may be reduced)
• Atazanavir, nelfinavir, rilpivirine (absorption reduced)
• Ketoconazole, itraconazole, iron tablets (absorption reduced)
• Methotrexate (high-dose — levels rise)
• Diazepam, phenytoin, warfarin, cilostazol, citalopram (levels may rise)

Usually mild symptoms such as drowsiness, blurred vision, confusion, dry mouth or headache. Treat symptomatically.

Store below 30°C in the original pack to protect from moisture.