Etoricoxib-60 Tablet

Selective COX-2 inhibitor (NSAID) for pain and inflammation:

• Osteoarthritis, rheumatoid arthritis, ankylosing spondylitis
• Acute gouty arthritis
• Short-term pain after dental surgery
• Chronic low back pain (in some countries)

Adults:

• Osteoarthritis: 30–60 mg once daily.
• Rheumatoid arthritis / ankylosing spondylitis: 60–90 mg once daily.
• Acute gout: 120 mg once daily for up to 8 days.
• Dental pain after surgery: 90 mg once daily for up to 3 days.
• Mild liver impairment: maximum 60 mg/day; moderate: 30 mg/day.
• Not for children under 16 years.
• Can be taken with or without food; use the lowest effective dose.

• Allergy to etoricoxib, aspirin or other NSAIDs
• Active peptic ulcer or stomach bleeding
• Ischaemic heart disease, stroke, peripheral arterial disease, heart failure (NYHA II–IV)
• Uncontrolled high blood pressure (above 140/90)
• Severe liver disease, kidney impairment with creatinine clearance below 30 ml/min
• Inflammatory bowel disease
• Pregnancy and breastfeeding

Common: swelling of legs (fluid retention), high blood pressure, dizziness, headache, indigestion, heartburn, stomach pain, diarrhoea, tiredness, raised liver enzymes.

Less common: palpitations, chest pain, shortness of breath, kidney problems.

Rare but serious: heart attack, stroke, stomach bleeding, liver failure, severe allergy and skin reactions.

• Check blood pressure within 2 weeks of starting and regularly afterwards.
• Higher cardiovascular risk with high doses and long use.
• Elderly and those with kidney, liver or heart problems need monitoring.

Contraindicated in pregnancy and breastfeeding.

• Warfarin (raises INR)
• Aspirin (more stomach bleeding)
• ACE inhibitors, ARBs, diuretics (kidney risk, less BP control)
• Lithium, methotrexate (levels rise)
• Rifampicin (lowers etoricoxib)
• Oral contraceptives and HRT (ethinylestradiol levels rise)

Stomach and kidney problems, heart effects. Seek medical care.

Store below 30°C, in the original pack.