Flomox 5 mg/ml Eye Drops

Fluoroquinolone antibiotic for:

• Community-acquired pneumonia, acute bacterial sinusitis and exacerbations of chronic bronchitis (when other antibiotics are unsuitable)
• Complicated skin and soft-tissue and intra-abdominal infections
• Mild to moderate pelvic inflammatory disease (with other drugs)
• Drug-resistant tuberculosis (combination therapy)
• Eye drops: bacterial conjunctivitis, prevention of infection after eye surgery

Adults: 400 mg once daily (oral or IV): sinusitis 7 days; bronchitis 5–10 days; pneumonia 7–14 days; skin infections 7–21 days.

Eye drops (0.5%): 1 drop 3 times daily for 7 days (or as directed).

• No dose change needed in kidney impairment.
• Take with water; separate from antacids, iron, zinc and calcium by at least 4–6 hours (or take moxifloxacin 4 hours before).
• Not for children and growing adolescents (oral/IV).

• Allergy to moxifloxacin or other quinolones
• Prolonged QT interval, low potassium, severe bradycardia, heart failure with low ejection fraction, history of arrhythmia
• Use with other QT-prolonging drugs
• Severe liver impairment
• Tendon problems with previous quinolones
• Pregnancy, breastfeeding, children (systemic)

Common: nausea, diarrhoea, dizziness, headache, QT prolongation (on ECG), raised liver enzymes.

Rare but serious: irregular heartbeat, tendon rupture, nerve damage, psychiatric reactions, seizures, severe liver injury, blood sugar changes, aortic aneurysm, severe skin reactions, C. difficile colitis.

Eye drops: temporary eye irritation, taste disturbance.

• Stop at first signs of tendon pain, numbness/tingling, palpitations or fainting, severe abdominal/back/chest pain.
• Elderly, steroids, diabetes, epilepsy: higher risks.
• Avoid strong sunlight.

Contraindicated in pregnancy and breastfeeding (systemic). Eye drops are generally acceptable.

• QT-prolonging drugs: antiarrhythmics, antipsychotics, some antidepressants, macrolides, antimalarials (avoid)
• Antacids, iron, zinc, sucralfate (reduce absorption)
• Warfarin (INR rise)
• Corticosteroids (tendon rupture)
• NSAIDs (seizures)

Dizziness, confusion, QT prolongation and arrhythmias. ECG monitoring; supportive care.

Store below 30°C. Eye drops: discard 4 weeks after opening.