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Amulet Pharmaceuticals Ltd.

Heligan 5 mg/5 ml Syrup

Promethazine Hydrochloride · 5 mg/5 ml

Medicine information: uses, dosage, side effects ↓

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Product details

Generic name
Promethazine Hydrochloride
Strength
5 mg/5 ml
Dosage form
Syrup
Manufacturer / brand
Amulet Pharmaceuticals Ltd.
SKU
246-0003-021

Medicine information: Promethazine Hydrochloride

Indications

Sedating phenothiazine antihistamine for:

  • Allergic conditions: hay fever, hives, itching, allergic reactions
  • Nausea and vomiting, motion sickness
  • Short-term insomnia and sedation (including before procedures)
  • Cough and cold preparations (with other ingredients)
  • Adjunct in anaphylaxis (injection)
Dosage & administration

Adults:

  • Allergy: 10–20 mg two to three times daily, or 25 mg at night.
  • Nausea / motion sickness: 25 mg at bedtime the night before travel, repeated after 6–8 hours as needed.
  • Sleep: 25–50 mg at bedtime.
  • Injection: 25–50 mg deep IM (health professional).

Children (not under 2 years):

  • 2–5 years: 5–15 mg daily (allergy) in 1–2 doses.
  • 5–10 years: 10–25 mg daily in 1–2 doses.
  • Do not use in children under 2 years (fatal breathing depression).
Contraindications
  • Children under 2 years
  • Coma, severe CNS depression
  • Use of MAO inhibitors within 14 days
  • Allergy to phenothiazines
  • Injection: not into an artery or under the skin (severe tissue damage)
Side effects

Common: drowsiness, dizziness, dry mouth, blurred vision, constipation, difficulty passing urine, next-day hangover effect.

Less common: confusion (especially elderly), restlessness, paradoxical excitation in children, sun sensitivity.

Rare but serious: breathing depression, seizures, jaundice, low blood counts, neuroleptic malignant syndrome, severe tissue injury from injection.

Precautions & warnings
  • Do not drive or operate machinery; avoid alcohol.
  • Elderly: increased risk of confusion and falls.
  • Asthma, glaucoma, enlarged prostate, epilepsy, liver disease, sleep apnoea: caution.
  • Stop 72 hours before allergy skin tests.
Pregnancy & breastfeeding

May be used occasionally for nausea in pregnancy on medical advice; avoid in the last 2 weeks (breathing depression and irritability in newborn). Avoid regular use while breastfeeding.

Interactions
  • Alcohol, opioids, benzodiazepines, other sedatives (deep sedation, breathing depression)
  • MAO inhibitors (contraindicated), tricyclic antidepressants, anticholinergics (more side effects)
  • Drugs prolonging QT
  • Metoclopramide (opposing effects)
Overdose

Deep sedation, confusion, seizures, breathing depression; children may become agitated and hallucinate. Emergency treatment.

Storage

Store below 30°C, protected from light.

This information is for general reference only. Always follow the dose prescribed by your doctor and ask a doctor or pharmacist before taking any medicine.

Same medicine from other companies

Promethazine Hydrochloride 5 mg/5 ml

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