Histalex 2 mg/5 ml Syrup

Sedating (first-generation) antihistamine for:

• Allergic rhinitis, hay fever, allergic conjunctivitis
• Urticaria (hives), itching, insect bites, drug or food allergy reactions
• Common cold symptoms (runny nose, sneezing)
• Injection: emergency treatment of allergic reactions and anaphylaxis (after adrenaline)

Adults and children over 12 years: 4 mg every 4–6 hours; maximum 24 mg/day.

Children 6–12 years: 2 mg every 4–6 hours (maximum 12 mg/day).

Children 2–5 years: 1 mg every 4–6 hours (maximum 6 mg/day).

Children 1–2 years: 1 mg twice daily (only if prescribed).

Injection: adults 10–20 mg IM/slow IV.

• May be taken with food. Not for children under 1 year (oral).

• Allergy to chlorpheniramine
• Children under 1 year
• Use of MAO inhibitors within the past 2 weeks

Common: drowsiness, sleepiness, poor concentration, dizziness, dry mouth, blurred vision, headache.

Less common: difficulty passing urine, constipation, nausea.

Children and elderly: paradoxical excitement, restlessness, confusion.

Rare: irregular heartbeat, blood disorders, seizures, allergic reactions.

• Causes drowsiness — do not drive or operate machinery; avoid alcohol.
• Use with caution in glaucoma, enlarged prostate, urinary retention, epilepsy, asthma, liver disease and the elderly.
• Many cough/cold mixtures contain antihistamines — avoid doubling up.

Avoid in the last trimester (may affect the newborn). Passes into breast milk — may cause drowsiness or irritability in the baby and reduce milk supply; non-sedating antihistamines are preferred.

• Alcohol, sedatives, opioids, sleeping pills (more drowsiness)
• MAO inhibitors, tricyclic antidepressants (more anticholinergic effects)
• Phenytoin (levels may rise)

Drowsiness, dry mouth, fast heartbeat, dilated pupils, confusion, hallucinations; seizures especially in children. Seek emergency care.

Store below 30°C, protected from light.