Ketofen 100 mg Tablet

NSAID for pain and inflammation:

• Rheumatoid arthritis, osteoarthritis, ankylosing spondylitis
• Acute gout
• Muscle, joint and soft-tissue injuries, back pain
• Period pain, pain after surgery
• Gel: local muscle and joint pain

Capsules/tablets (adults): 50 mg two to three times daily, or 100 mg twice daily (maximum 200 mg/day).

Sustained/modified release: 100–200 mg once daily with food.

Injection: 100 mg IM once or twice daily for up to 3 days (health professional).

Gel 2.5%: apply 2–4 times daily to the painful area for up to 7 days.

• Take with or after food.
• Elderly, kidney or liver impairment: lowest effective dose.
• Not recommended for children under 15.

• Allergy to ketoprofen, aspirin or other NSAIDs
• Active or past recurrent peptic ulcer or bleeding
• Severe heart, kidney or liver failure
• Last 3 months of pregnancy
• Gel: photosensitivity history, sensitivity to fenofibrate, octocrylene sunscreens or thiaprofenic acid

Common: indigestion, nausea, stomach pain, diarrhoea or constipation, headache, dizziness.

Less common: rash, fluid retention, raised blood pressure.

Rare but serious: stomach bleeding/ulcer, kidney injury, heart attack/stroke (high doses long-term), severe allergy, bronchospasm.

Gel: photosensitivity reactions — severe skin reactions on sun exposure of treated skin (even up to 2 weeks after stopping).

• Gel: protect treated skin from sun and sunbeds during use and for 2 weeks afterwards; wash hands after applying.
• Avoid combining with other NSAIDs.
• Heart disease, hypertension, asthma, kidney disease, elderly: caution.

Avoid in the first 6 months unless advised; contraindicated in the last 3 months. Avoid while breastfeeding (ibuprofen preferred).

• Other NSAIDs, aspirin, steroids (stomach bleeding)
• Warfarin, antiplatelets, SSRIs (bleeding)
• ACE inhibitors, ARBs, diuretics (kidney injury, less effect)
• Lithium, methotrexate (toxicity)
• Probenecid (raises levels)

Drowsiness, nausea, vomiting, stomach pain; rarely seizures, kidney failure. Seek medical care.

Store below 30°C, protected from light.