Krimisol 40 mg Tablet

Anthelmintic (worm medicine) for:

• Roundworm (Ascaris) infection
• Hookworm infection (often as part of combination treatment)
• Also used on specialist advice as an immunomodulator (e.g. steroid-sensitive nephrotic syndrome in children)

Roundworm — single dose:

• Adults: 150 mg once.
• Children: 2.5–3 mg/kg once (as a guide: 1–3 years 40 mg; 4–7 years 50–80 mg; 8–14 years 80–100 mg).
• Dose may be repeated after 7–14 days if needed.

Nephrotic syndrome (specialist): 2–2.5 mg/kg on alternate days.

• Take after a meal; no laxative or fasting needed.

• Allergy to levamisole
• Pre-existing low white cell count (agranulocytosis)

Single dose: usually well tolerated — nausea, vomiting, abdominal pain, dizziness, headache.

Prolonged use: rash, flu-like symptoms, taste changes, agranulocytosis (low white cells — fever, sore throat), vasculitis, rarely brain inflammation (leukoencephalopathy).

• Long-term use needs regular blood counts; report fever, sore throat or mouth ulcers.
• Rheumatoid arthritis and Sjögren's syndrome: higher risk of blood problems.
• Kidney or liver disease: caution.

Avoid in the first trimester; use later only if needed. Avoid while breastfeeding.

• Alcohol (disulfiram-like reaction)
• Warfarin (increased effect — monitor)
• Phenytoin (levels may rise)

Nausea, vomiting, dizziness, confusion, seizures in large overdose. Seek medical care.

Store below 30°C, protected from light.