Limaryl 3 mg Tablet

Sulphonylurea for type 2 diabetes:

• Lowers blood sugar when diet and exercise are not enough
• Used alone or with metformin, other tablets or insulin

Adults: start 1 mg once daily with breakfast (or the first main meal); increase by 1 mg every 1–2 weeks according to blood sugar; usual 1–4 mg once daily; maximum 6 mg (some guidelines 8 mg) daily.

Elderly / kidney impairment: start 1 mg, increase carefully.

• Take with breakfast; do not skip meals afterwards.
• Swallow with water.

• Type 1 diabetes, diabetic ketoacidosis, diabetic coma
• Severe kidney or liver impairment
• Allergy to glimepiride, other sulphonylureas or sulphonamides
• Pregnancy and breastfeeding

Most important: low blood sugar (sweating, shaking, hunger, palpitations, confusion, fits if severe).

Common: nausea, stomach discomfort, diarrhoea, headache, dizziness.

Less common: weight gain, temporary visual changes, rash, itching, sun sensitivity.

Rare: liver problems, blood disorders, low sodium, severe allergy.

• Learn hypoglycaemia symptoms; carry sugar.
• Care with alcohol, fasting, heavy exercise, illness.
• G6PD deficiency (haemolysis risk).
• Monitor blood sugar, HbA1c, and periodically liver and blood counts.

Not recommended in pregnancy or breastfeeding; insulin is used.

• Fluconazole, miconazole, clarithromycin, fluoroquinolones, ACE inhibitors, NSAIDs, alcohol (more hypoglycaemia)
• Beta-blockers (mask hypoglycaemia)
• Steroids, thiazides, thyroid hormones, oral contraceptives (raise blood sugar)
• Rifampicin (reduces effect)
• Warfarin (effect may change)

Severe, long-lasting low blood sugar — emergency care, hospital monitoring.

Store below 30°C.