Nysol 1 Lac Unit/ml Suspension

Polyene antifungal (not absorbed from the gut) for:

• Oral suspension: oral thrush (mouth and throat candidiasis), including in infants and denture wearers; prevention in high-risk patients
• Cream/ointment/powder: cutaneous candidiasis (skin folds, nappy rash with Candida)
• Vaginal tablets/cream: vaginal candidiasis

Oral suspension 100,000 units/ml:

• Adults and children: 1 ml (100,000 units) four times daily after food, held in the mouth as long as possible before swallowing; continue for 48 hours after the thrush clears (usually 7 days).
• Infants: 1 ml four times daily — apply half to each side of the mouth with a dropper.
• Severe/immunocompromised: up to 5 ml four times daily.

Skin: apply 2–4 times daily until 1 week after healing.

Vaginal: 100,000 units nightly for 14 days.

• Allergy to nystatin

Usually well tolerated. Oral: nausea, vomiting, diarrhoea with high doses, mouth irritation. Skin: local irritation. Rare: allergic reactions, Stevens–Johnson syndrome.

• Clean dentures and soak them overnight; treat the denture-fitting surface.
• For breastfed infants with thrush, the mother's nipples may also need treatment.
• Suspension contains sugar (dental caries with long use).
• Not effective for systemic fungal infections.

Safe in pregnancy and breastfeeding (not absorbed).

No significant interactions (not absorbed).

Large oral doses may cause nausea and diarrhoea only.

Store below 25–30°C. Shake the suspension well; use within the time stated after opening.