Pregabac 25 Capsule

Medicine for nerve pain, anxiety and seizures:

• Neuropathic pain: diabetic neuropathy, post-herpetic neuralgia (after shingles), spinal cord injury pain
• Fibromyalgia
• Generalised anxiety disorder
• Add-on treatment for partial (focal) seizures

Adults: start 75 mg twice daily (or 50 mg three times daily); may increase to 150 mg twice daily after 3–7 days; maximum 300 mg twice daily (600 mg/day).

Elderly or kidney impairment: lower doses according to kidney function.

• Can be taken with or without food.
• Do not stop suddenly — reduce gradually over at least 1 week.
• Not recommended for children.

• Allergy to pregabalin

Very common/common: dizziness, drowsiness, headache, weight gain, increased appetite, blurred vision, dry mouth, constipation, swelling of hands/feet, unsteadiness, poor concentration, mood changes.

Less common: low mood, confusion, sexual problems.

Rare but serious: breathing problems (with opioids or in lung disease), severe allergy (face/throat swelling), suicidal thoughts, heart failure in susceptible people, misuse and dependence.

• Can cause drowsiness and dizziness — do not drive until you know how it affects you; avoid alcohol.
• Risk of misuse/dependence, especially with a history of drug abuse.
• Combining with opioids (e.g. tramadol) or sedatives increases the risk of breathing problems.
• Tell your doctor about depression or suicidal thoughts.

Avoid in pregnancy unless clearly needed; effective contraception advised. Passes into breast milk — not recommended while breastfeeding.

• Opioids, benzodiazepines, alcohol, other sedatives (more drowsiness, breathing depression)
• Oxycodone, lorazepam (added effects on thinking and movement)
• ACE inhibitors (more risk of swelling)

Drowsiness, confusion, agitation, restlessness; seizures and coma rarely. Seek emergency care.

Store below 30°C.