Rapofen 400 mg Tablet

NSAID painkiller, anti-inflammatory and fever reducer for:

• Fever and pain in adults and children (including after vaccination)
• Headache, migraine, toothache, period pain
• Muscle and joint pain, sprains, back pain
• Rheumatoid arthritis, osteoarthritis
• Gel: local muscle and joint pain

Adults and children over 12 years: 200–400 mg every 6–8 hours as needed; maximum 1,200 mg/day without medical advice (up to 2,400 mg/day on prescription for arthritis).

Children (over 3 months and over 5 kg): 5–10 mg/kg every 6–8 hours; maximum 30 mg/kg/day (e.g. suspension 100 mg/5 ml — 6–12 months 2.5 ml three times daily; 1–3 years 5 ml three times daily; 4–6 years 7.5 ml three times daily; 7–9 years 10 ml three times daily).

• Take with or after food or milk.
• Use the lowest effective dose for the shortest time; see a doctor if fever lasts more than 3 days.

• Allergy to ibuprofen, aspirin or other NSAIDs (asthma, hives, rhinitis)
• Active or past recurrent peptic ulcer/bleeding
• Severe heart, kidney or liver failure
• Last 3 months of pregnancy
• Dehydration in children (vomiting/diarrhoea) — risk of kidney injury
• Chickenpox (risk of severe skin infections) — paracetamol is preferred

Common: indigestion, heartburn, nausea, stomach pain, diarrhoea, headache, dizziness.

Less common: rash, fluid retention, raised blood pressure, worsening asthma in sensitive people.

Rare but serious: stomach bleeding or ulcer (black stools, vomiting blood), kidney injury, heart attack/stroke (high doses long-term), severe allergy and skin reactions, aseptic meningitis.

• Elderly, people with ulcers, heart disease, high blood pressure, kidney or liver disease, or asthma: use with caution or avoid.
• Do not combine with other NSAIDs.
• Stay well hydrated.

Avoid in the first 6 months unless advised; contraindicated in the last 3 months. Compatible with breastfeeding at usual doses (preferred NSAID).

• Other NSAIDs and aspirin (stomach bleeding; may reduce aspirin's heart protection)
• Anticoagulants, antiplatelets, SSRIs (bleeding)
• ACE inhibitors, ARBs, diuretics (kidney risk, less BP control)
• Lithium, methotrexate (toxicity)
• Corticosteroids (ulcers)

Nausea, vomiting, stomach pain, drowsiness, ringing in ears; at high doses seizures, kidney failure, metabolic acidosis. Seek medical care.

Store below 30°C.