Rosuva 10 mg Tablet

Statin medicine that lowers cholesterol:

• High LDL cholesterol, mixed dyslipidaemia, high triglycerides (with diet)
• Prevention of heart attack and stroke in people at high cardiovascular risk
• Familial hypercholesterolaemia (adults and children 6 years and over, specialist use)
• Slowing progression of atherosclerosis

Adults: start 5–10 mg once daily; may increase after 4 weeks to 20 mg; 40 mg only for severe cases under specialist care.

Asian patients, kidney impairment, or risk factors for muscle problems: start 5 mg; maximum 20 mg/day.

Children (familial): 5–20 mg once daily by age, specialist use.

• Take at any time of day, with or without food, at the same time daily.

• Allergy to rosuvastatin
• Active liver disease, unexplained raised liver enzymes
• Severe kidney impairment (creatinine clearance below 30 ml/min)
• Muscle disease (myopathy), use with ciclosporin
• Pregnancy and breastfeeding
• 40 mg dose: Asian patients, hypothyroidism, alcohol abuse, kidney impairment, use with fibrates

Common: headache, muscle aches, stomach pain, constipation, nausea, weakness, dizziness, raised blood sugar.

Less common: itching, rash, protein in urine (high doses).

Rare but serious: muscle damage (rhabdomyolysis), liver inflammation, memory problems, severe skin reactions, new diabetes in at-risk people.

• Report unexplained muscle pain, weakness or dark urine.
• Liver tests before and 3 months after starting.
• Kidney function at higher doses.

Contraindicated in pregnancy and breastfeeding.

• Ciclosporin (contraindicated)
• Gemfibrozil and other fibrates (muscle risk; limit to 10–20 mg)
• HIV protease inhibitors (limit dose)
• Warfarin (raises INR — monitor)
• Antacids (take rosuvastatin 2 hours before)
• Fusidic acid (avoid together)

No specific treatment; supportive care, monitor liver and CK.

Store below 30°C, in the original pack.