Trifix 100 mg/5 ml Suspension

Oral third-generation cephalosporin antibiotic for:

• Urinary tract infections
• Typhoid (enteric) fever
• Throat, tonsil, sinus and middle-ear infections
• Bronchitis and other chest infections
• Uncomplicated gonorrhoea

Adults and children over 12 years (or over 50 kg): 400 mg daily, as a single dose or 200 mg every 12 hours.

Typhoid: usually 200–400 mg twice daily (about 20 mg/kg/day) for 10–14 days, as prescribed.

Gonorrhoea: single 400 mg dose (or as per current guidelines).

Children (6 months–12 years): 8 mg/kg/day as one dose or in 2 divided doses.

• Can be taken with or without food.
• Reduce the dose if creatinine clearance is below 20 ml/min.

• Allergy to cefixime or other cephalosporins
• History of severe allergic reaction to penicillins

Common: diarrhoea, loose stools, abdominal pain, nausea, indigestion, wind.

Less common: headache, dizziness, rash, itching, vaginal thrush.

Rare: severe allergic reaction, C. difficile colitis, severe skin reactions, liver or kidney problems, blood disorders.

• Tell your doctor about any penicillin allergy.
• Stop and seek help if severe or bloody diarrhoea occurs.
• Lower dose in severe kidney impairment.
• Complete the full course.

No evidence of harm; used in pregnancy when clearly needed. Not known if it passes into breast milk in meaningful amounts — use with caution while breastfeeding.

• Warfarin and other anticoagulants (bleeding risk may rise)
• Carbamazepine (levels may rise)
• Nifedipine (may increase cefixime levels)

Stomach upset (nausea, vomiting, diarrhoea). Treat symptoms; seek medical advice.

Store below 30°C, dry and protected from light. Reconstituted suspension: use within 14 days (or as stated on the pack).