Trusert A 80/5 Tablet

Combination of an ARB and a calcium-channel blocker for high blood pressure not controlled by either medicine alone, or to replace separate tablets.

Adults: one tablet once daily — telmisartan 40 mg + amlodipine 5 mg, 40/10, 80/5 or 80/10 mg.

• Usually start 40/5 mg; increase after 1–2 weeks if needed. Maximum 80/10 mg daily.
• Take at the same time each day, with or without food.
• Mild–moderate liver impairment: telmisartan maximum 40 mg.
• Not for children.

• Pregnancy
• Biliary obstruction, severe liver impairment
• Shock, severe aortic stenosis, unstable heart failure after a heart attack
• Use with aliskiren in diabetes or kidney impairment
• Allergy to telmisartan or dihydropyridines

Common: ankle swelling, dizziness, headache, flushing, tiredness.

Less common: low blood pressure, palpitations, back pain, raised potassium/creatinine, nausea, sleepiness.

Rare but serious: angioedema, kidney failure, severe low blood pressure, liver problems.

• Check kidney function and potassium periodically.
• Avoid dehydration; caution in heart failure.
• Diabetes on insulin: watch sugar.

Contraindicated in pregnancy. Not recommended while breastfeeding.

• Potassium supplements, spironolactone, salt substitutes (high potassium)
• NSAIDs (reduced effect, kidney risk)
• Lithium (toxicity)
• ACE inhibitors, aliskiren (avoid combining)
• Simvastatin (limit to 20 mg); clarithromycin, itraconazole, grapefruit (raise amlodipine)
• Digoxin (monitor)

Severe low blood pressure, fast or slow heartbeat. Emergency care.

Store below 30°C in the original blister.