Vergon 5 mg/5 ml Syrup
Prochlorperazine Mesilate · 5 mg/5 ml
Medicine information: uses, dosage, side effects ↓
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Product details
- Generic name
- Prochlorperazine Mesilate
- Strength
- 5 mg/5 ml
- Dosage form
- Syrup
- Manufacturer / brand
- Opsonin Pharma Limited
- SKU
- 025-0674-018
Medicine information: Prochlorperazine
Indications
Phenothiazine antiemetic for:
- Severe nausea and vomiting (including migraine-related)
- Vertigo and dizziness from Ménière's disease, labyrinthitis
- Short-term treatment of anxiety; schizophrenia (higher doses, specialist)
Dosage & administration
Nausea/vomiting (adults): 5–10 mg two to three times daily; acute: 20 mg then 10 mg after 2 hours.
Vertigo: 5 mg three times daily, increased to max 30 mg/day; reduce gradually.
Buccal tablets 3 mg: 1–2 tablets twice daily placed between gum and upper lip.
Injection: 12.5 mg deep IM, then oral after 6 hours.
Children: over 10 kg (usually 1 year+) — 250 microgram/kg two to three times daily only for severe vomiting of known cause; avoid in young children.
- Use the shortest course possible.
Contraindications
- Children under 10 kg / under 1 year
- Reduced consciousness, CNS depression
- Bone marrow depression, phaeochromocytoma
- Allergy to phenothiazines
Side effects
Common: drowsiness, dizziness, dry mouth, blurred vision, constipation.
Less common: acute dystonia (involuntary muscle spasms of face/neck/eyes — more in young people and children), restlessness (akathisia), parkinsonism, low blood pressure.
Rare but serious: tardive dyskinesia (long use), neuroleptic malignant syndrome (fever, rigidity, confusion), QT prolongation, jaundice, low white cells, skin photosensitivity.
Precautions & warnings
- May cause drowsiness — avoid driving and alcohol.
- Elderly (falls, low BP; increased stroke/death risk in dementia), Parkinson's disease, epilepsy, prostate enlargement, glaucoma, heart disease: caution.
- Avoid strong sunlight.
- Stop and seek help for muscle spasms or high fever with stiffness.
Pregnancy & breastfeeding
Avoid unless needed (newborn movement and withdrawal symptoms if used late in pregnancy). Avoid while breastfeeding where possible.
Interactions
- Alcohol, sedatives, opioids, antihistamines (more drowsiness)
- Other QT-prolonging drugs (arrhythmia)
- Anticholinergics (more side effects); levodopa (opposing effects)
- Antihypertensives (low BP); lithium (neurotoxicity)
Overdose
Drowsiness, low blood pressure, movement disorders, seizures, arrhythmias, low temperature. Emergency care.
Storage
Store below 30°C, protected from light.
This information is for general reference only. Always follow the dose prescribed by your doctor and ask a doctor or pharmacist before taking any medicine.
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